Junior R&D PET Radiochemist

London, England, United Kingdom | Full-time

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Junior R&D PET Radiochemist

This is an exciting opportunity to work within the Invicro R&D Radiochemistry Team responsible for the development of novel PET biomarkers and for supporting their evaluation in preclinical imaging studies.

The successful candidate will contribute to contract-research studies, being responsible for delivering radiochemistry projects and supporting PET imaging studies in a fast-paced environment.

Background

Based in London, Boston and New Haven, Invicro specialises in molecular and functional imaging studies to support novel pharmaceutical product development. Invicro has two cyclotrons and 24 hot cells enabling imaging with a wide range of C11 and F18 labelled PET radiotracers and is located on the Hammersmith Hospital/Imperial College London site in West London.

 Role:

The successful candidate will be responsible for:

  • Managing and delivering carbon-11 and fluorine-18 radiochemistry projects (radiolabeling feasibility and tracer implementation) to high scientific standards and timelines.
  • Developing and implementing radiolabelling methods to enable the use and/or characterization in preclinical species of known or novel radiopharmaceuticals/radiotracers.
  • Providing scientific and technical input on radiolabeling feasibility strategies.
  • Preparing technical reports and scientific presentations.
  • Writing and maintaining document records to ensure compliance with GxP standards.
  • Managing own work area in shared laboratories, being accountable for the safety of these areas.

 To be considered for this position you will have:

  • Ph.D in relevant field (e.g. organic chemistry, medicinal chemistry) with preferably knowledge in PET radiochemistry and prior experience working with carbon-11 and/or fluorine-18 radioisotopes.
  • Ability to independently plan and design own experiments, interpret the data and draw conclusions.
  • Ability to identify problems, troubleshoot and create and implement workable solutions.
  • Knowledge of reaction optimization, purification, development of suitable quality control procedures (e.g. HPLC, GC, LC-MS, etc) and radiometabolite analysis.
  • Understanding of the unique aspects pertaining to the radiation safety, GxP and other aspects related to the development of novel and established PET radiotracers.
  • Good understanding of pre-clinical and clinical PET imaging is preferred.
  • Knowledge of radiochemistry automation and synthesis devices with particular relevance to PET is preferred.
  • Strong innovation skills to develop new approaches and seek continuous methodologies improvement.
  • Ability to set priorities and determine requirements so multiple tasks are achieved and multiple projects are efficiently managed in a fast-paced environment.
  • Ability to work effectively in a multidisciplinary team and to assimilate a working knowledge of areas outside of their core competency.
  • Ability to work effectively with vision, integrity, flexibility

Personal Characteristics and other requirements

The successful candidate must have excellent verbal and written communication skills, strong analytical skills, a logical approach to problem solving and high standards of attention to detail.

Competitive Salary & Benefits

Contributory Pension, Bonus, Private Medical Insurance, Life Assurance & Flexible Benefits options

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.

 

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