Scientist, In Vivo Pharmacology

Boston, Massachusetts, United States | Full-time

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Make an impact at a dynamic and growing life sciences company. Invicro seeks a scientist to be a leading member of our in vivo research team. 

Overview:

The open scientist position is one that will technically execute and manage to conclusion all in vivo pharmacology studies in support of pre-clinical discovery imaging. These studies will include rat and mouse biodistribution, disease model development, efficacy, and tox like studies. The qualified candidate will be charged with management of the colony and the day to day of in vivo staff, as well as communicate data and project updates. This position will provide an opportunity for growth in leadership skills and exposure to cutting-edge sponsor research projects.

Responsibilities

  • Overseeing the technical operation of a small species animal care facility (ACF)
  • Training and managing a staff of 3-4 to best allocate resources for study execution, including oversight of husbandry
  • Experience developing pharmacological models and associated techniques in allotted timelines
  • Critically assess working protocols for experimental details
  • Highly functioning set of classical skills required, including but not limited:
    • Test article administration (all routes), CNS administration a plus
    • Compound handling and formulation
    • Tissue resection and micro-dissection
    • Rodent veterinary care and husbandry
    • Biological sampling procedures
    • Survival surgery techniques
  • Model development and execution of:
    • Efficacy studies
    • Biodistribution studies
    • Pharmacokinetic studies
    • Toxicokinetic studies
    • Xenograft models
  • Experience working within an IACUC to implement and ensure compliance of animal use protocols and SOPs.
  • Procurement of and management of the colony
  • Ability to multi-task own responsibilities and communicate details of your work with scientists of all levels

Qualifications and Skills:

  • Bachelor Degree in Animal Science or a related field
  • 5+ years of experience in the biomedical/pharmaceutical research industry performing responsibilities noted above
  • Ability to multi-task effectively is essential
  • Strong written and oral communication skills
  • Comfort with various computer operating systems and programs
  • Weekend work required
  • Ability to lift 50 pounds

Preferred but not required qualifications:

  • Having worked across multiple therapeutic disciplines is an advantage
  • Understanding of the challenges of intra-lab, cross-functional communication and execution
  • Knowledge of CRO operations and sponsor interactions a plus
  • Knowledge of the application of radioisotopes in a drug discovery setting
  • Familiarity with small animal imaging modalities
  • In vitro assay and cell culture applications
  • Knowledge of rare disease and fragile animal models

 

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.