Sr. Associate Scientist, in vitro

Boston, Massachusetts, United States | Full-time

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Overview:

Make an impact at a dynamic and growing life sciences company. Invicro (Boston site) seeks a junior level scientist to be a contributing member of our in vivo research team.  

The Sr. Associate Scientist position is one that will support preclinical small species medical imaging studies. It is required that candidate has a minimum of 5-10 years of experience in a laboratory research setting and conducts duties in a semi-independent manner. The position requires experience in culturing established cell lines and isolating primary normal cells using established sterile tissue culture techniques. Prior experience with protein work; lysate preparation, quantitation, SDS-PAGE, Western blot analysis is required. Experience with flow cytometry/FACS and analyzing data, ELISA, and basic molecular biology techniques (DNA and RNA quantitation, PCR) is desired. Any prior experience in techniques such as immunohistochemistry, analytical pharmacology, animal modeling/pharmacology and assisting with experiments with rodents, ranging from basic injections to surgical procedures, is a plus.  This position will provide an opportunity for growth with respect to scientific scope and overall laboratory capabilities. A qualified applicant is enthusiastic about biomedical research, able and willing to rapidly learn new skills and begin applying them immediately.             

Responsibilities:

  • Cell/tissue culture using established sterile culture techniques (viability assessment, cell passage, and culture for in vivo inoculation)
  • Use of various biochemical techniques, including SDS-PAGE and Western blots, to support ongoing projects
  • Familiarity with and ability to perform techniques like flow cytometry, Immunohistochemistry, DNA/RNA work, analytical chemistry
  • Maintaining a cell culture suite and understanding supplies critical to execution
  • Ability to execute work independently and share results and conclusions to project stakeholders
  • Willingness to aid in routine animal husbandry and simple procedures including providing clinical observations and contributing to the operation of a small species animal care facility (ACF)
  • Stocking supplies and laboratory maintenance

Qualifications and Skills:

  • Bachelor’s degree in Biological sciences paired with 5-10 years of research experience
  • Comprehension of working scientific protocols and ownership of role specific tasks
  • Strong organizational skills with ability to manage complex experimental designs
  • Ability to multi-task
  • Comfort with various computer operating systems and programs
  • Strong written and oral communication skills
  • Some weekend work required
  • Ability to lift 50 pounds

Preferred but not required qualifications:

  • Knowledge of aseptic technique, experimental design, and pharmacology or small animal imaging in the context of pharmaceutical research
  • Experience with rodent animal facility operations
  • Experience in offering technical support to preclinical pharmacology studies, including but not limited to:
    • Subcutaneous cell inoculation or tumor fragment implantation for xenograft models
    • Injections and infusions
    • Necropsies for biodistribution studies
    • Anesthesia and euthanasia support
    • Compound dosing for treatment studies

 

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.