Sr. Associate Scientist, in vitro

Boston, Massachusetts, United States | Full-time

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Overview:

Make an impact at a dynamic and growing life sciences company. Invicro (Boston site) seeks a junior level scientist to be a contributing member of our in vivo research team.  

The open associate scientist position is one that will support in vitro and preclinical small species medical imaging studies. It is required that the candidate has a minimum of 1 - 2 years of experience in a laboratory research setting and conducts duties in a semi-independent manner. The position requires experience in culturing established cell lines and isolating primary normal cells using established sterile tissue culture techniques. Prior experience with radioligand binding assays (cell-based, bead-based, etc), lysate preparation/quantitation, cell radiolabeling, cell-based assays, protein detection methods (Western blot, electrophoresis, etc), and basic molecular biology techniques (DNA and RNA quantitation, PCR) is desired. Experience with immunohistochemistry, analytical pharmacology, other in vitro assays, animal handling/modeling/pharmacology and assisting with rodent experiments ranging from injections to surgical procedures, is a plus.  This position will provide an opportunity for growth with respect to scientific scope and overall laboratory responsibilities. A qualified applicant is enthusiastic about biomedical research, able and willing to rapidly learn new skills and begin applying them immediately.       

Responsibilities:

  • Conduct tissue culture using established aseptic techniques (viability assessment, cell passage, and culture for in vivo inoculation)
  • Execute radioligand binding assays using cells, magnetic beads, or purified proteins
  • Collaborate with radiochemistry to radiolabel cells for injection
  • Support ongoing projects by assisting with other biochemical, molecular biology, and cellular techniques
  • Assist pharmacology team with rodent pharmacology studies: injections, necropsy, surgical procedures, husbandry, clinical observations, etc   
  • Stock supplies, maintain laboratory equipment, ensure compliance with safety protocols, contribute to operation of small species animal care facility (ACF)

Qualifications and Skills:

  • Bachelor’s degree in Biological sciences supplemented by one or more years of research experience or an equivalent combination of education and experience.
  • Strong organizational skills with ability to manage complex experimental designs and work independently
  • Ability to multi-task
  • Curious, eager, and open to learning new skills
  • Strong written and oral communication skills
  • Some weekend work required
  • Ability to lift 50 pounds

Preferred but not required qualifications:

  • Experience in offering technical support to preclinical pharmacology studies, including but not limited to:
    • Subcutaneous cell inoculation or tumor fragment implantation for xenograft models
    • Injections and infusions
    • Necropsies for biodistribution studies
    • Anesthesia and euthanasia support
    • Compound dosing for treatment studies
  • Knowledge of small animal imaging in the context of pharmaceutical research
  • Experience with rodent animal facility operations

 

Invicro is an equal opportunities employer and positively encourages applications from suitably qualified and eligible candidates regardless of sex, race, disability, age, sexual orientation, gender reassignment, religion or belief, marital status, or pregnancy and maternity.